Failure to Adjuvant Therapy After Pancreatic Resection for Pancreatic Cancer: a Real Life Scenario
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 317
- 试验地点
- 1
- 主要终点
- Rate of patients who fail to receive adjuvant therapy and reasons for that
研究概览
简要总结
This study aims to evaluate the rate of patients submitted to pancreatic resection for pancreatic cancer, who fail to access to adjuvant therapy or do not complete adjuvant therapy. The purpose is to give an overview concerning the most frequent conditions and/or reasons associated with failure or omission of adjuvant therapy.
详细描述
This prospective observational study will evaluate all patients submitted to pancreatic resection for pancreatic cancer.
The rate of omission to adjuvant therapy and rate of failure of completion of adjuvant therapy will be evaluated as primary outcomes. As secondary outcomes, survival analyses will be performed to investigate whether these factors influence prognosis, that will be evaluated through a disease free survival analysis at 18-months. Epidemiological and perioperative data will be analyzed to identify conditions associated with the primary outcomes.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Histologic diagnosis of pancreatic cancer
排除标准
- •Non exocrine pancreatic tumors
- •Periampullary malignancies
结局指标
主要结局
Rate of patients who fail to receive adjuvant therapy and reasons for that
时间窗: 6 months
The amount of patients who will not receive adjuvant therapy after pancreatic resection for malignancy (when do indication exists) will be recorded
Rate of patients who fail to complete adjuvant therapy and reasons for that
时间窗: 9 months
The amount of patients who will not complete adjuvant therapy after pancreatic resection for malignancy will be recorded
次要结局
- Disease free survival of patients enrolled(18 months)
研究者
Salvatore Paiella, MD
Salvatore Paiella, MD, Università di Verona
Universita di Verona