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Clinical Trials/NCT01280760
NCT01280760
Completed
N/A

Impact of Neurally Adjusted Ventilator Assist (NAVA) Mode on Patient Ventilator Asynchrony Using Non-invasive Ventilation (NAVA-NIV)

Pierre and Marie Curie University1 site in 1 country16 target enrollmentJanuary 2011
ConditionsWeaning Period

Overview

Phase
N/A
Intervention
Not specified
Conditions
Weaning Period
Sponsor
Pierre and Marie Curie University
Enrollment
16
Locations
1
Primary Endpoint
Triggering delay
Status
Completed
Last Updated
12 years ago

Overview

Brief Summary

Non-invasive ventilation (NIV) has been proposed to reduce the incidence of ventilatory dysfunction following mechanical ventilation weaning. However, the nasogastric tube reduces the airtightness of the facial mask used to perform non-invasive ventilation and induces air leaks. The presence of leaks at the patient-mask interface can increase the risk of patient-ventilator asynchrony, which in turn leads to increase patient discomfort. Neurally adjusted ventilatory assist (NAVA)could contribute to decreasing asynchrony. Its principle is to record the diaphragmatic electrical activity and to control the ventilator. The investigators hypothesized driving the ventilator based on a neural signal (diaphragm electrical activity) would reduce patient-ventilator asynchronies in NIV

Registry
clinicaltrials.gov
Start Date
January 2011
End Date
May 2011
Last Updated
12 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
Pierre and Marie Curie University
Responsible Party
Principal Investigator
Principal Investigator

Matthieu SCHMIDT

Dr

Pierre and Marie Curie University

Eligibility Criteria

Inclusion Criteria

  • Patients with increased risk of post-extubation ventilatory dysfunction following invasive mechanical ventilation weaning.

Exclusion Criteria

  • Contra-indication to non-invasive ventilation
  • Pregnancy

Outcomes

Primary Outcomes

Triggering delay

Time Frame: Every inspiration, for 10 minutes

Duration between the onset of neural inspiration and the onset of insufflation

Secondary Outcomes

  • Cycling off delay(Every inspiration, for 10 minutes)

Study Sites (1)

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