Impact of Neurally Adjusted Ventilator Assist (NAVA) Mode on Patient Ventilator Asynchrony Using Non-invasive Ventilation (NAVA-NIV)
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Weaning Period
- Sponsor
- Pierre and Marie Curie University
- Enrollment
- 16
- Locations
- 1
- Primary Endpoint
- Triggering delay
- Status
- Completed
- Last Updated
- 12 years ago
Overview
Brief Summary
Non-invasive ventilation (NIV) has been proposed to reduce the incidence of ventilatory dysfunction following mechanical ventilation weaning. However, the nasogastric tube reduces the airtightness of the facial mask used to perform non-invasive ventilation and induces air leaks. The presence of leaks at the patient-mask interface can increase the risk of patient-ventilator asynchrony, which in turn leads to increase patient discomfort. Neurally adjusted ventilatory assist (NAVA)could contribute to decreasing asynchrony. Its principle is to record the diaphragmatic electrical activity and to control the ventilator. The investigators hypothesized driving the ventilator based on a neural signal (diaphragm electrical activity) would reduce patient-ventilator asynchronies in NIV
Investigators
Matthieu SCHMIDT
Dr
Pierre and Marie Curie University
Eligibility Criteria
Inclusion Criteria
- •Patients with increased risk of post-extubation ventilatory dysfunction following invasive mechanical ventilation weaning.
Exclusion Criteria
- •Contra-indication to non-invasive ventilation
- •Pregnancy
Outcomes
Primary Outcomes
Triggering delay
Time Frame: Every inspiration, for 10 minutes
Duration between the onset of neural inspiration and the onset of insufflation
Secondary Outcomes
- Cycling off delay(Every inspiration, for 10 minutes)