SCED - Wisdom Enhancement for Post-Stroke Depression

Not Applicable

Active, not recruiting

• Conditions: Post-stroke Depression
• Interventions: Other: Timeline Intervention

• Registration Number: NCT06451965
• Lead Sponsor: University of East Anglia

Brief Summary

One-third of stroke survivors experience post-stroke depression, but there are currently no official guidelines for supporting them. Researchers aim to investigate whether the wisdom enhancement timeline technique can reduce depression in stroke survivors. The investigators also want to understand how this technique positively impacts mood, identity, self-esteem, and wisdom. The study will involve nine stroke survivors from the National Health Service (NHS) to gain insights into effective ways to support those with post-stroke depression.

Detailed Description

One-third of stroke survivors have post-stroke depression. Finding ways to help them feel more positive after such a challenging event can be tricky. Right now, there are no official guidelines on the best way to support post-stroke depression, and research into this is still growing. That is why the investigators want to see if the wisdom enhancement timeline can improve the mood and overall well-being of people who have had a stroke.

In this study, the investigators have two goals. First, the investigators want to see if the wisdom enhancement timeline technique can reduce depression in stroke survivors. Second, the investigators aim to discover how this technique brings positive mood changes.

The main question the investigators want to answer

1. Does enhancing wisdom through the timeline technique improve psychological outcomes (mood, identity, self-esteem) in post-stroke depressed individuals?

2. In post-stroke depressed individuals, is the improvement in wisdom the first indicator of subsequent improvements in identity, self-esteem, and mood?

It is hypothesised that wisdom will improve first following the session where wisdom is applied. This will then be followed by either identity or self-esteem, with mood improving last.

To carry out this study, the investigators will work with three stroke survivors receiving care from the National Health Service (NHS). By focusing on this smaller group, the investigators hope to gain insights into the effectiveness of the technique in reducing depression and enhancing the lives of stroke survivors. This study is essential as it could help the investigators understand the best way to support those with post-stroke depression.

Study Timeline

• Study Start: 2023-09-01
• Status Verified: 2024-05
• Study First Submitted: 2024-05-29
• Study First Submitted QC: 2024-06-04
• Study First Posted: 2024-06-11
• Last Update Submitted: 2025-02-24
• Last Update Posted: 2025-02-27
• Primary Completion: 2025-10-01
• Study Completion: 2025-10-01

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: All
• Target Recruitment: 3

Inclusion Criteria

• Had a stroke.
• Those who self-report as having difficulties with depression to a clinician.
• Have sufficient cognitive and communication abilities for informed consent and active engagement

Exclusion Criteria

• Under the age of 18. Because this is the age when they are treated as an adult by UK law.
• Severe cognitive impairments or mental health difficulties that would hinder task engagement or provide informed consent.
• Medical instability jeopardising consistent participation or well-being.
• Significant risk concerns regarding safety to themselves or others.
• Substance use/dependency impacting adherence.
• Prescribed psychotropic medication less than 3 months ago.
• Currently involved in research.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Treatment Phase	Timeline Intervention	After the baseline phase, participants will enter the treatment phase. This phase will consist of 6 weekly and hourly therapy sessions to deliver the wisdom enhancement timeline intervention.

Primary Outcome Measures

Name	Time	Method
Visual Analogue Scale (VAS)	Daily from baseline to the end of the 10-week study.	Four questions, asking participants to rate on a 0-10 scale

Secondary Outcome Measures

Name	Time	Method
Patient Health Questionnaire-9	Assessed at baseline and at the end of the 10-week study.	Standardised questionnaire to measure depression

Trial Locations

Locations (1)

University of East Anglia; 🇬🇧 Norwich, United Kingdom