CTRI/2025/12/098962尚未招募不适用
A randomised double blinded control trial between fentanyl and remifentanil in attenuating hemodynamic response to laryngoscopy and intubation in patients undergoing surgery under general anesthesia.
North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences1 个研究点 分布在 1 个国家目标入组 40 人开始时间: 2026年1月1日最近更新:
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- which drug prevents increase in heart rate and blood pressure better
研究概览
简要总结
study hypothesis: Remifentanil is superior to fentanyl in blunting hemodynamic response to laryngoscopy and intubation during general anesthesia
This study aims to see if inj Remifentanil is superior to inj fentanyl in blunting hemodynamic stress response to laryngoscopy ad intubation
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •Age- 18 to 65 years
- •ASA I,II and III
- •Both sexes
- •surgeries requiring General anesthesia with orotracheal intubation with direct laryngoscopy.
排除标准
- •pregnant and lactating women
- •previous sensitivity to fentanyl, remifentanil, propofol, egg or soya bean
- •patients on beta blockers
- •chronic use of alcohol, sedatives or opioid abuse.
结局指标
主要结局
which drug prevents increase in heart rate and blood pressure better
时间窗: At baseline and then at minute interval 1,3,5,10 and 15.
次要结局
- side effects of the medications(at minute interval 5,15,30,60 post surgery till transfer out from recovery area.)
研究者
Dr Newstar Syiemiong
North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences
研究点 (1)
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