To determine whether presence of Human papilloma virus(HPV) in biopsy specimens affect overall staging and clinical outcome in oropharygeal cancer patients

Not Applicable

• Conditions: Health Condition 1: C109- Malignant neoplasm of oropharynx,unspecified

• Registration Number: CTRI/2020/03/024062
• Lead Sponsor: MULTIDISCIPLINARY RESEARCH UNIT MRU GOVT MEDICAL COLLEGE PATIALA

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 17 October 2022

Recruitment & Eligibility

• Status: Closed to Recruitment of Participants
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

1.Biopsy proven non metastatic squamous cell carcinoma of oropharynx

2.Karnofsky Performance Status � 80

3.Patient fit for concurrent chemotherapy

4.Patientââ?¬•s willingness to give informed consent.

Exclusion Criteria

1.Age <18 years

2.Previously treated cases of carcinoma oropharynx (with Surgery/Chemotherapy/radiation)

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
a)To determine incidence of HPV p16 positive cases of carcinoma oropharynx <br/ ><br>registered in the department of radiotherapy of our institute. <br/ ><br>b) To analyze difference in the local control and overall survival in HPV p16 positive <br/ ><br>and negative patients when stratified in accordance to AJCC 7th and 8th staging <br/ ><br>system. <br/ ><br>Timepoint: Assesement done at yearly basis

Secondary Outcome Measures

Name	Time	Method
To determine prognostic factors for overall survival in HPV p16 positive and <br/ ><br>negative patients <br/ ><br>Timepoint: Assesement done at yearly basis