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Clinical Trials/NCT03700775
NCT03700775
Completed
Not Applicable

Remote Hypertension Management Using Home Blood Pressure Telemonitoring and a Standardized Treatment Protocol

University of Mississippi Medical Center1 site in 1 country120 target enrollmentSeptember 17, 2018
ConditionsHypertension

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Hypertension
Sponsor
University of Mississippi Medical Center
Enrollment
120
Locations
1
Primary Endpoint
Adverse events
Status
Completed
Last Updated
5 years ago

Overview

Brief Summary

This is a prospective study evaluating the feasibility and safety of remote hypertension management using a central telemonitoring program among patients with elevated blood pressure (BP) at the University of Mississippi Medical Center (UMMC).

Detailed Description

Patients with elevated BP, identified by the electronic medical record, will be recruited for study enrollment. Patients will be mailed a telemonitoring kit including an electronic tablet equipped with a wireless BP cuff that transmits measurements directly to the UMMC electronic medical record and monitored by the UMMC Center for Telehealth. Patients will participate in a 6 month intervention period during which they will transmit daily BP recordings with regular contact by a Telehealth nurse coordinator who will provide education and encourage healthy lifestyle habits. Every 2 weeks BP medications will be adjusted according to an evidence-based treatment algorithm managed by the Center for Telehealth pharmacist using a standardized physician-approved protocol. Data analysis will track metrics of study enrollment, study completion, safety, therapeutic intensification, and BP change from baseline.

Registry
clinicaltrials.gov
Start Date
September 17, 2018
End Date
June 22, 2020
Last Updated
5 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Age greater than 18 years
  • Patient of UMMC clinician approving the study
  • At least 2 clinic encounters in the past 12 months with systolic BP ≥ 140 mmHg and/or diastolic BP ≥ 90 mmHg

Exclusion Criteria

  • Stage 4 or 5 chronic kidney disease
  • Systolic heart failure (LVEF \<50%) or major cardiovascular event (MI, stroke) within 3 months
  • Resistant hypertension (prescribed 3 or more antihypertensive medications at target doses) or known secondary cause of hypertension
  • Pregnancy or inability/unwillingness to use birth control for women of child-bearing potential
  • Institutionalized, dementia, limited life expectancy, uncontrolled mental illness, substance abuse, or other conditions that would prohibit ability to perform regular home BP monitoring

Outcomes

Primary Outcomes

Adverse events

Time Frame: 6 months

Adverse event data will primarily be collected through self-report during each nursing coordinator contact with the patient. Participants will report any hospitalization longer than 12 hours, emergency room visits, or some-day clinic visits and reasons for those visits since the prior nurse coordinator encounter. Study staff will obtain and review medical records related to all adverse events including: deaths, hospitalizations, major cardiac events, incident kidney failure, and urgent evaluations for hypertension, hypotension, loss of consciousness or fainting, allergic reactions, hives, and angioedema. These events are evaluated for severity, expectedness, and potential relatedness to the intervention and study participation.

Secondary Outcomes

  • Antihypertensive medication adjustments(6 months)
  • BP control rates(12 months)

Study Sites (1)

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