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临床试验/NCT03999255
NCT03999255已完成不适用

REDUCING KIDNEY MOTION: OPTIMIZING ANESTHESIA AND COMBINING RESPIRATORY SUPPORT FOR RETROGRADE INTRARENAL SURGERY: A PILOT STUDY

St. Petersburg State Pavlov Medical University1 个研究点 分布在 1 个国家目标入组 38 人开始时间: 2017年11月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
38
试验地点
1
主要终点
Kidney motion assessed by the endourologist during retrograde intrarenal surgery

研究概览

简要总结

Patients undergoing retrograde intrarenal surgery for kidney stones from November 2017 to May 2018 were prospectively recruited to participate in the study. In each case after the beginning of general anesthesia with mechanical ventilation surgeons were asked to assess the mobility of the operative field and conditions for laser lithotripsy according to the developed questionnaire scale. The questionnaire consisted of 5 degrees of assessment of kidney mobility and each question was scored from 1 to 5, 1 being very mobile (extremely poor conditions for dusting) and 5 completely immobile (Ideal conditions for dusting). After this assessment modified technique of general anesthesia was applied called combined respiratory support which consisted of reduction of tidal volume to 250-300 ml and respiratory rate to 4-5 per minute with transcatheter high frequency jet ventilation through endotracheal tube with a respiratory cycle frequency of 300 per minute and maintained during retrograde intrarenal surgery. At the beginning of combined respiratory approach, surgeons were once again asked to assess the mobility of the operative field and the conditions for laser lithotripsy. Main ventilation parameters were recorded and compared in both regimens.

研究设计

研究类型
Interventional
干预模型
Sequential
主要目的
Treatment
盲法
None

入排标准

性别
All
接受健康志愿者
否

入选标准

  • •Kidneys stones with indications for retrograde intrarenal surgery

排除标准

  • •Patients with ASA class of greater than 3
  • •Patients with active urinary tract infection were excluded from the study

研究组 & 干预措施

Patients undergoing intrarenal surgery

Experimental

干预措施: combined respiratory support (CRS) (Procedure)

结局指标

主要结局

Kidney motion assessed by the endourologist during retrograde intrarenal surgery

时间窗: duration of RIRS Surgery

a questionnaire was implemented in order to assess surgeon's feedback on novel technique. This was done in 2-step fashion in every patient and each patient served his own control: first, after the beginning of GA with MV in the mode of normal ventilation the questionnaire was implemented and surgeons were asked to assess the mobility of the operative field and the decency of conditions for laser lithotripsy. Second, novel CRS technique was then instituted and maintained throughout RIRS. Before lithotripsy itself surgeons were once again asked to assess the mobility of the operative field and conditions for laser lithotripsy according to the previously mentioned questionnaire.

次要结局

未报告次要终点

研究者

发起方
St. Petersburg State Pavlov Medical University
申办方类型
Other
责任方
Principal Investigator
主要研究者

nariman.gadjiev

Head of Endourology

St. Petersburg State Pavlov Medical University

研究点 (1)

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