Better Outcomes in Living donor liver transplantation with Terlipressi
Phase 2
- Conditions
- Health Condition 1: null- Adult End stage liver disease patients undergoing living donor liver transplantation
- Registration Number
- CTRI/2013/10/004072
- Lead Sponsor
- Global Hospital health City
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 40
Inclusion Criteria
Adult patients undergoing first living donor liver transplantation for primary liver disease
GRWR <1.2
Exclusion Criteria
Combined liver-kidney transplants
Significant pre-operative renal dysfunction (eGFR <50)
Significant uncorrected coronary artery disease
Urgent transplants
Re-transplants
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Portal pressureTimepoint: Before recipient hepatectomy <br/ ><br>After arterial reperfusion
- Secondary Outcome Measures
Name Time Method Blood loss <br/ ><br>Blood product requirement <br/ ><br>Intraoperative urine output <br/ ><br>Intraoperative lactate <br/ ><br>Intraoperative inotropic requirement <br/ ><br>Postoperative renal dysfunction <br/ ><br>Postoperative complications <br/ ><br>ICU stay <br/ ><br>Hospital stay <br/ ><br>Adverse effects of trial medicationTimepoint: Intraoperative <br/ ><br>Postoperative