A pilot study to assess the effect of beta blockade on exercise capacity and BNP levels in patients with predominantly diastolic heart failure
Not Applicable
Completed
- Conditions
- Cardiovascular: Heart failureCirculatory SystemHeart failure
- Registration Number
- ISRCTN77645264
- Lead Sponsor
- Record Provided by the NHSTCT Register - 2006 Update - Department of Health
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 40
Inclusion Criteria
A total of 40 patients with evidence or history of clinical heart failure, ejection fraction of >45% and raised plasma BNP levels.
Exclusion Criteria
1. History of asthma / COPD
2. Hypotension, patients with significant bradycardia
3. BMI>30
4. Intolerant of beta-blockers, patients with constrictive pericarditis, with severe peripheral vascular disease, patients having suffered myocardial infarction within 3 months prior to enrolment
5. Pregnant women
6. Use of any investigational drug within 2 weeks of enrolment
7. Any recent changes in cardiac medications
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method