ISRCTN77645264
Completed
未知
A pilot study to assess the effect of beta blockade on exercise capacity and BNP levels in patients with predominantly diastolic heart failure
Record Provided by the NHSTCT Register - 2006 Update - Department of Health0 sites40 target enrollmentSeptember 29, 2006
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- Record Provided by the NHSTCT Register - 2006 Update - Department of Health
- Enrollment
- 40
- Status
- Completed
- Last Updated
- 9 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •A total of 40 patients with evidence or history of clinical heart failure, ejection fraction of \>45% and raised plasma BNP levels.
Exclusion Criteria
- •1\. History of asthma / COPD
- •2\. Hypotension, patients with significant bradycardia
- •3\. BMI\>30
- •4\. Intolerant of beta\-blockers, patients with constrictive pericarditis, with severe peripheral vascular disease, patients having suffered myocardial infarction within 3 months prior to enrolment
- •5\. Pregnant women
- •6\. Use of any investigational drug within 2 weeks of enrolment
- •7\. Any recent changes in cardiac medications
Outcomes
Primary Outcomes
Not specified
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