Study on reduction of salivary virus by Sodium Lauryl Diethylenediaminoglycinate on COVID-19

Phase 1

• Conditions: COVID-19 infection; C000657245

• Registration Number: JPRN-jRCTs051210107
• Lead Sponsor: Matsuyama Akifumi

Brief Summary

Thirty-one participants were enrolled into this study. In terms of the virus removing effect from the oral cavity by mouthwash and gargling, the lauryldiaminoethylglycine sodium gargling group tended to have a higher virus removing effect from the oral cavity than the water gargling group (p=0.065). In particular, in gargling but not mouthwash of oral cavity, the lauryldiaminoethylglycine sodium-containing group had a significantly higher effect of removing the virus from the oral cavity than the water-cont

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2021-10-13
• Study Completion: 2022-01-08
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Complete
• Sex: Female
• Target Recruitment: 31

Inclusion Criteria

(1) Subjects whose age at the time of obtaining consent is more than 20 years
(2) Sex; female
(3) quarantine at the hotel
(4) Meets all of 1)-3) below
1) Subjects whose Asymptomatic/mild case (without respiratory sympton nor dyspnea) has at least one RT-PCR test positive for SARS-CoV-2 from pharyng eal swab, nasopharyng eal swab or saliva.
2) Subjects who can gargle
3) Subjects who are on the first day of admission to the accommodation treatment facility and plan to perform accommodation treatment for 6 days or more
(5) Subjects who have obtained written consent voluntarily to participate in the trial

Exclusion Criteria

Garg ling with sodium lauryl diethylendiaminoglycine before entry

Study & Design

• Study Type: Interventional
• Study Design: Not specified