Differentiation of mutations in toll-like receptors 2 and 4 and their correlation to the classic and modern infect parameters in critically ill patients

• Conditions: Critically ill patients; R57.2; A41; Septic shock; Other sepsis

• Registration Number: DRKS00003171
• Lead Sponsor: niv.-Klinik für Anästhesiologie m.S. operative Intensivmedizin, CVK/CCMCharité-Universitätsmedizin Berlin

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2009-12-31
• Study Start: 2011-07-08
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 149

Inclusion Criteria

Consecutive intensive care treatment of more than 36 h in three anestesiologically managed intensive care units during serial three months periods

Exclusion Criteria

1. age less than 18 years
2. pregnancy

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
severity of sepsis

Secondary Outcome Measures

Name	Time	Method
1.duration of mechanical ventilation <br>2.duration of sepsis, <br>3. duration of severe sepsis, <br>4. duration of septic shock, <br>5. mortality <br>6. duration of ICU stay<br>7. time-to-onset of infections