Respiratory Muscles and Inspiratory Muscle Training

Not Applicable

Completed

• Conditions: Respiratory Muscles; Breathing Exercises
• Interventions: Other: Inspiratory Muscle Training; Other: Sham Inspiratory Muscle Training

• Registration Number: NCT02243527
• Lead Sponsor: University of British Columbia

Brief Summary

The effects of inspiratory muscle training (IMT) remain controversial. Many studies have examined the effect IMT has on exercise performance, but any changes to the body that come from IMT have yet to be looked at.

This study will look at how someone breathes can change after IMT. Understanding how IMT changes the body can help us use IMT in different treatments.

Detailed Description

Not available

Study Timeline

• Study Start: 2014-09
• Study First Submitted: 2014-09-16
• Study First Submitted QC: 2014-09-17
• Study First Posted: 2014-09-18
• Primary Completion: 2016-07
• Study Completion: 2016-07
• Results First Submitted: 2018-11-08
• Status Verified: 2019-04
• Results First Submitted QC: 2019-04-15
• Last Update Submitted: 2019-04-15
• Results First Posted: 2019-07-05
• Last Update Posted: 2019-07-05

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 25

Inclusion Criteria

• Recreationally active, 'Moderate' or 'High' category on International Physical Activity Questionnaire Short form questionnaire
• Able to read and understand English
• Pulmonary function within normal limits

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Exclusion Criteria

• History of or currently smoking
• History or current symptoms of cardiopulmonary disease (including asthma and exercise induced asthma)
• Currently participating and training in a sport at a provincial, national, or international level
• Ulcer or tumor in the esophagus, a nasal septum deviation, or recent nasopharyngeal surgery
• Allergies to latex or local anesthetic
• Contraindications to exercise testing

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Inspiratory Muscle Training	Inspiratory Muscle Training	-
Sham-Control Inspiratory Muscle Training	Sham Inspiratory Muscle Training	Inspiratory muscle training at a low intensity meant to elicit no physiological changes.

Primary Outcome Measures

Name	Time	Method
Diaphragm Electromyography	Post Intervention - ie. immediately after 5 weeks of inspiratory muscle training	Using a multipair esophageal electrode catheter we will determine any changes to the electric activity of the diaphragm.; Diaphragm electromyography (EMG) has been expressed as %max. This unit is determined as the ratio of average EMG value (uV) divided by the maximal EMG activity (uV) generated during a maximal respiratory maneuver (inspiratory capacity during exercise).

Secondary Outcome Measures

Name	Time	Method
Accessory Respiratory Muscle Activation	Post-intervention - ie. immediately after 5 weeks of inspiratory muscle training	Using surface electromyography to determine the activation patterns of accessory respiratory muscles (scalene and sternocleidomastoid).; Data are expressed as %max. This value is determined by taking the average electromyography (EMG) activity divided by the maximal EMG activity generated during a maximal inspiratory maneuver (inspiratory capacity during exercise).

Trial Locations

Locations (1)

Centre for Heart Lung Innovation; 🇨🇦 Vancouver, British Columbia, Canada