Clinical study of the changes in platelet function and coagulation in insulin tolerance test
Not Applicable
- Conditions
- diabetes mellitus
- Registration Number
- JPRN-UMIN000019899
- Lead Sponsor
- Kagoshima University Graduate School of Medical and Dental Sciences
- Brief Summary
Ten subjects were included. Along with the hypoglycemia, epinephrine were significantly changed. There was a correlation between the decrease in plasma glucose and the change of epinephrine Further,the change of epinephrine was correlated with change of T10 and OT.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
Not provided
Exclusion Criteria
65 years of age or older patients, Patients with a history of ischemic heart disease and seizures Patients who has oral anti-platelet drug or anticoagulant drug
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method AUC10, area under curve until 10 min for PL chip on T-TAS(Total Thrombus-formation Analysis System) and plasma catecholamines at 0min,15min,30min,60min, 90min, 120min before and after insulin load
- Secondary Outcome Measures
Name Time Method 1)plasma PAI-1(plasminogen activator inhibitor-1) 2) P-selectin and PAC-1 by flowcytometry