Impact of a Multifaceted Program to Prevent Postoperative Delirium in the Elderly

Not Applicable

Terminated

• Conditions: Postoperative Delirium
• Interventions: Behavioral: Multifaceted prevention program HELP(Hospital Elder Life Program)

• Registration Number: NCT01316965
• Lead Sponsor: Hospices Civils de Lyon

Brief Summary

Postoperative delirium is common in the elderly and is associated with a significant increase in mortality, complications, length of hospital stay and admission in long care facility. Several interventions have proved their effectiveness to prevent it but their combination within a multifaceted intervention needs to be assessed using rigorous methodology based on randomized study design. CONFUCIUS trial aims to measure the impact of a multifaceted program on the prevention of postoperative delirium in elderly.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2011-03-15
• Study First Submitted QC: 2011-03-15
• Study First Posted: 2011-03-16
• Study Start: 2011-04
• Status Verified: 2017-05
• Primary Completion: 2017-05
• Study Completion: 2017-05
• Last Update Submitted: 2017-05-24
• Last Update Posted: 2017-05-30

Recruitment & Eligibility

• Status: TERMINATED
• Sex: All
• Target Recruitment: 175

Inclusion Criteria

• Male or female subject aged over 75 years
• Admission for a scheduled surgery (i.e. all oncologic digestive surgery , ureterostomy, nephrectomy or cystectomy, total hip or knee replacement)
• Participation agreement

Exclusion Criteria

• Patients with a progressive and/or poorly managed psychiatric pathology (patients with stabilized depression could be included in the study)

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
multifaceted prevention program	Multifaceted prevention program HELP(Hospital Elder Life Program)	-

Primary Outcome Measures

Name	Time	Method
Postoperative delirium rate within 7 days after surgery	7 days after surgery

Secondary Outcome Measures

Name	Time	Method
Length of hospital stay	Hospital discharge
Mortality 6 months after surgery	6 months after surgery
Mean delirium intensity within 7 days after surgery	7 days after surgery
Postoperative complications 30 days after surgery incidence	30 days after surgery
Feasibility of the multidisciplinary prevention program	24 months

Trial Locations

Locations (1)

Hospices Civils de Lyon-Hôpital des Charpennes; 🇫🇷 Villeurbanne, France