MedPath

Evolution of the Therapeutic Care in Metastatic Breast Cancer From 2008

Recruiting
Conditions
Metastatic Breast Cancer
Registration Number
NCT03275311
Lead Sponsor
UNICANCER
Brief Summary

The Epidemiological Strategy and Medical Economic (ESME) Ovarian cancer Data Platform is a multi-center real life database using a retrospective data collection process (18 FCCCs over 20 sites). This database compiles data from Patient's Electronic medical records (EMR), inpatient Hospitalisation records and Pharmacy records.

Detailed Description

This database compiles data from Patient's Electronic medical records (EMR), inpatient Hospitalisation records and Pharmacy records.

Patient Database: Patient-related data integrates data from non-structured sources (electronic medical records), such as patient medical records and reports of multidiscipline team meetings. It can provide information on patient demographics, primitive tumour, relapses, pathology reports, metastatic disease, therapeutic care/settings and withdrawal reasons when applicable, and clinical events.

Treatment Database: Pharmacy records-related data is a structured database including all data pertaining to medications prescribed and dispensed by pharmacies within each French Comprehensive Cancer Centers (FCCC), specifically chemotherapy and co-prescriptions. It does not contain information on products that are prescribed or delivered outside of the center. From each center's pharmacy database, information on systemic treatment patterns (dates, pharmaceutical forms, treatment protocols, etc.) can be obtained.

Hospitalization Database: Hospitalisation-related data is a structured and systematic database that contains all medical data reported related to any hospitalisation in the FCCC, and is used to bill the French National Health Insurance Fund (Assurance Maladie). It provides information on patient entry and discharge dates as well as diagnostic and therapeutic procedures performed, including radiotherapy and surgery.

Data imported into the final database are controlled, recoded, and harmonized before import according to a data management plan. All coding procedures are predefined by the data manager. There is no transmission of individual data; all data are centralized within each center using a shared anonymous format. All data are exclusively obtained retrospectively; no attempts are made to recover non available data from the patient's medical record by contacting healthcare providers or patients.

ESME MBC Data Platform aims to be a clinical and therapeutic database centralising existing and available data from different sources used in the FCCCs.

Recruitment & Eligibility

Status
RECRUITING
Sex
All
Target Recruitment
38000
Inclusion Criteria

Not provided

Read More
Exclusion Criteria

Not provided

Read More

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Describe the evolution of therapeutic carebaseline

Patient characteristics, tumor characteristics and treatment patterns

Secondary Outcome Measures
NameTimeMethod
Describe the impact of therapeutic strategies on survival criteriaFrom date of diagnosis or first treatment until the date of first documented progression or date of death from any cause. Follow up until 2023.

Progression free survival

Trial Locations

Locations (20)

Institut Bergonié

🇫🇷

Bordeaux, France

Institut de Cancérologie de l'Ouest - Paul Papin

🇫🇷

Angers, France

Centre François Baclesse

🇫🇷

Caen, France

Centre Jean Perrin

🇫🇷

Clermont-ferrand, France

Centre Léon Bérard

🇫🇷

Lyon, France

Centre Georges-François Leclerc

🇫🇷

Dijon, France

Centre Oscar Lambret

🇫🇷

Lille, France

Institut Paoli-Calmettes

🇫🇷

Marseille, France

Institut régional du Cancer Montpellier / Val d'Aurelle

🇫🇷

Montpellier, France

Institut de cancérologie de l'Ouest - René Gauducheau

🇫🇷

Nantes, France

Institut Curie

🇫🇷

Paris, France

Centre Henri Becquerel

🇫🇷

Rouen, France

Centre Eugène Marquis

🇫🇷

Rennes, France

Institut Curie - Hôpital René Huguenin

🇫🇷

Saint-Cloud, France

Institut Gustave Roussy

🇫🇷

Villejuif, France

Centre Paul Strauss

🇫🇷

Strasbourg, France

Institut Claudius Regaud

🇫🇷

Toulouse, France

Institut de Cancérologie de Lorraine

🇫🇷

Nancy, France

Centre Antoine Lacassagne

🇫🇷

Nice, France

Institut Jean Godinot

🇫🇷

Reims, France

© Copyright 2025. All Rights Reserved by MedPath