Effect of Levonorgestrel Intrauterine System on Hemoglobin Level

Not Applicable

Not yet recruiting

• Conditions: Hemoglobin; Deficiency

• Registration Number: NCT06935968
• Lead Sponsor: Assiut University

Brief Summary

To study the effect of LNG-IUS on improving iron status in reproductive-aged women presenting for contraception.

Detailed Description

Women come to family planning clinic to insert levonorgestrel intrautrine system and take a blood sample from her to analyse hemoglobin level

Study Timeline

• Status Verified: 2025-04
• Study First Submitted: 2025-04-07
• Study First Submitted QC: 2025-04-12
• Last Update Submitted: 2025-04-12
• Study First Posted: 2025-04-20
• Last Update Posted: 2025-04-20
• Study Start: 2025-05-01
• Primary Completion: 2026-05
• Study Completion: 2026-07

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: Female
• Target Recruitment: 100

Inclusion Criteria

1. The study will include married women attending the outpatient clinics of the forementioned health facilities for contraception counseling
2. Age between 18 and 45 years
3. Women who choose LNG_IUS for contraception
4. Any parity including nulliparous

Exclusion Criteria

• 1.Women with any inherited hemoglobinopathy (thalassemia, sickle cell anemia) or acquired hemolytic anemia 2.Women with sever iron deficiency anemia requiring immediate treatment 3.Women with any contraindication to Mirena insertion (pelvic inflammatory disease, cervical or vaginal infection, cervical cancer) 4. Any uterine abnormality making LNG_IUS insertion difficult (septate uterus or fibroid distorting the cavity) 5. Women within 6 months of delivery

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
Change of blood haemoglobin level from time of insertion to 6 months after insertion	6 months	To know the effect of LNG-IUDs on hemoglobin level after insertion

Secondary Outcome Measures

Name	Time	Method
Change of serum ferritin level from time of insertion to 6 months after insertionPrevalence of iron deficiency and iron deficiency anemia in women requiring contraception in our community	6 months	To know the effect of LNG-IUDs in serum ferritin