Immunity After COVID-19 Vaccination
- Conditions
- Tunis Military Hospital Staff Vaccinated Against Covid 19
- Registration Number
- NCT04924855
- Lead Sponsor
- General Administration of Military Health, Tunisia
- Brief Summary
The purpose of the research is to evaluate kinetic after vaccination to the COVID-19 coronavirus by measurements of specific and neutralizant antibodies for spike antigenic sequences .
This work will allow us to follow the efficacy and tolerance of the vaccine over a year, to evaluate the antibody profile, their kinetics, the fraction of neutralising antibodies and will also allow us to understand the attitudes to be taken to ensure the best protection for our staff
- Detailed Description
Our objective is to follow the hospital staff after vaccination, for this we will include two groups of participants:
G1: vaccinated staff who did not contract the virus (at the date of vaccination) and who had a serology \<0 at least at D7 of the date of vaccination dose 1 (known serological value) G2: vaccinated personnel who have contracted the virus with a PCR + and who have positive serology at least at D7 of the date of vaccination (known serological value)
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 300
RB-approved informed consent, age 18 years or older, male or female, anyone considering COVID-19 vaccination or anyone that has received COVID-19 vaccination.
Subjects can enroll at anytime after vaccination even though they may not have enrolled before vaccination.
Sampling Frequency and timing: Up to 8 total samples in 12 months -
Exclusion: Failure to provide informed consent
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Vaccine effectiveness 1 year antibody kinetics
- Secondary Outcome Measures
Name Time Method the tolerance of the vaccine 1 year post-vaccination adverse event
Trial Locations
- Locations (1)
HMPIT vaccination committee
🇹🇳Tunis, Please Select..., Tunisia