Fractional CO2 Laser Combined With Platelet Rich Plasma Fluid Versus Gel Form in Treatment of Atrophic Acne Scars: A Randomized Clinical Trial
试验速览
- 阶段
- 早期 1 期
- 发起方
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- Test which combination is more effective, fractional laser with PRP fluid or fractional laser with PRP gel
研究概览
简要总结
This study is to test the efficacy of fractional laser combined with either PRP fluid or PRP gel in the treatment of atrophic acne scars
详细描述
The study will include 20 patients, treated with fractional CO2 laser plus PRP fluid on one side of the face and fractional CO2 laser plus PRP gel on the other side.
Choosing which side of the face will be injected with PRP fluid and which side will be injected with PRP gel will be chosen according to a randomization table for each patient.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age above 18
- •Both genders
- •Skin types III - V
- •Willingness and ability to comply with the requirements of the protocol
- •Atrophic acne scars
排除标准
- •Patients with active acne
- •Patients with herpes labialis, bacterial infections, other infections such as HBV. HCV or HIV.
- •Oral isotretinoin use in the previous 6 months
- •Pregnancy
- •Tendency to keloid formation
- •Patients with severe systemic illness or malignancy
- •Patients with connective tissue diseases
- •Patients with bleeding tendencies or any other hematological disease
结局指标
主要结局
Test which combination is more effective, fractional laser with PRP fluid or fractional laser with PRP gel
时间窗: one year
Effectiveness of each combination will be measured with OCT, depth of a fixed scar on each side of the face will be measured at baseline and then compared with 1 month after the last session and 3 months after the last session
次要结局
未报告次要终点
研究者
Yasmine Ahmed Abd El-Maguid El-Hadidy
Dermatology Resident
Kasr El Aini Hospital