Mediterranean Diet in Familial Mediterranean Fever: Is Fatty Liver Affected by Addition of Elliptical Aerobic Exercise
Trial Snapshot
- Phase
- Not Applicable
- Status
- Recruiting
- Sponsor
- Cairo University
- Enrollment
- 40
- Locations
- 1
- Primary Endpoint
- aspartate transaminase
Study Overview
Brief Summary
Familial Mediterranean fever (FMF) affect liver and causes some dysfunctions including non-alcoholic fatty liver.. still exercise and diet limitation is the treatment for this case
Detailed Description
Familial Mediterranean fever (FMF women with fatty liver) will be collected to be cateogarized to group I or group II. Every group OF FMF will contain 20 FMF women. Both groups will follow their colchicine (traditional daily drug therapy for FMF) in addition to Mediterranean diet for six months. Group I will also perform elliptical aerobic exercise (this exercise will be applied for 40 minutes three times weekly and this exercise will be maintained for 6 months)
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- Single (Investigator)
Eligibility Criteria
- Ages
- 30 Years to 55 Years (Adult)
- Sex
- Female
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •familial Mediterrean fever women
- •obese women
- •women who have fatty live (non alcoholic type)
Exclusion Criteria
- •cardiac patients
- •respiratory disease
- •renal disease
Arms & Interventions
group number 1
Familial Mediterranean fever (FMF women ) will be collected in this group. the group OF FMF will contain 20 FMF women. the group will follow their colchicine (traditional daily drug therapy for FMF) in addition to Mediterranean diet for six months. also, this group, Group I, will also perform elliptical aerobic exercise (this exercise will be applied for 40 minutes three times weekly and this exercise will be maintained for 6 months)
Intervention: exercise plus diet restriction (Behavioral)
group number 2
Familial Mediterranean fever (FMF women ) will be collected in this group. the group OF FMF will contain 20 FMF women. the group will follow their colchicine (traditional daily drug therapy for FMF) in addition to Mediterranean diet for six months.
Intervention: diet restriction (Behavioral)
Outcomes
Primary Outcomes
aspartate transaminase
Time Frame: it will be measured after 6 months
it is a hepatic enzyme
Secondary Outcomes
- erythrocyte sedimentation rate(it will be measured after 6 months)
- alanine transaminase(it will be measured after 6 months)
- body mass index(it will be measured after 6 months)
- waist circumference(it will be measured after 6 months)
- high density lipoprotein(it will be measured after 6 months)
- triglycerides(it will be measured after 6 months)
- cholesterol(it will be measured after 6 months)
- low density lipoprotein(it will be measured after 6 months)
- c reactive protein(it will be measured after 6 months)
Investigators
Ali Mohamed Ali ismail
lecturer of physical therapy for Cardiovascular, Respiratory disorder and Geriatrics, Faculty of Physical Therapy, Cairo University
Cairo University