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Clinical Trials/NCT02738086
NCT02738086
Completed
N/A

Physical Activity Behavior Change for Older Veterans After Dysvascular Amputation

VA Office of Research and Development1 site in 1 country31 target enrollmentJuly 1, 2016

Overview

Phase
N/A
Intervention
Not specified
Conditions
Amputation
Sponsor
VA Office of Research and Development
Enrollment
31
Locations
1
Primary Endpoint
Retention Rate
Status
Completed
Last Updated
6 years ago

Overview

Brief Summary

This pilot study will use mobile-health technology to deliver an intervention designed for lasting physical activity behavior change. The study will assess the feasibility of using the Physical Activity Behavior Change(PABC) intervention for Veterans with lower limb amputation. This intervention will be delivered using wrist-worn wearable activity sensors and a home-based tablet computer to allow real-time physical activity feedback and video interface between the participants and the therapist.

Detailed Description

This pilot study will assess the feasibility of using the Physical Activity Behavior Change(PABC) intervention for Veterans with dysvascular lower limb amputation. In addition, preliminary efficacy of the PABC intervention will be assessed using a two-group randomized cross-over design. Testing will occur at baseline (pre-intervention), three months (end of intervention), and six months. The primary aim is to determine feasibility of using the PABC intervention with Veterans who have dysvascular amputation by measuring: 1. participant retention 2. dose goal attainment 3. participant acceptability 4. safety The secondary aim is to preliminary assess efficacy of the PABC intervention by measuring accelerometer-based physical activity and self-report disability effect sizes.

Registry
clinicaltrials.gov
Start Date
July 1, 2016
End Date
February 22, 2019
Last Updated
6 years ago
Study Type
Interventional
Study Design
Crossover
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Lower limb amputation 1-5 years prior to enrollment
  • Type 2 Diabetes Mellitus and/or
  • Peripheral Artery Disease
  • Ambulatory using a lower limb prosthesis
  • English speaking

Exclusion Criteria

  • Traumatic or cancer-related etiology of the lower limb amputation
  • Unstable heart condition, including:
  • unstable angina
  • uncontrolled cardiac dysrhythmia
  • acute myocarditis
  • acute pericarditis
  • Uncontrolled hypertension
  • Acute systemic infection
  • Decisionally challenged volunteers
  • Recent cerebral vascular accident (within two years)

Outcomes

Primary Outcomes

Retention Rate

Time Frame: 3 months

Retention rate will be measured as the percent of participants enrolled in the intervention who complete the intervention.

Dose Goal Attainment

Time Frame: 3 months

Dose goal attainment will be measured as the percent of participants in the intervention phase of the study who meet the dose goal of an average 3% increase in daily steps.

Acceptability

Time Frame: 3 months

Acceptability will be measured using the mean score of the Intrinsic Motivation Inventory - Interest / Enjoyment Subscale. The scores range from 1 to 7, with higher numbers indicating higher acceptability, and a null value of 5.0.

Study-Related Adverse Events

Time Frame: 3 months

Safety will be assessed as differences in rates of study-related adverse events between GROUP 1 and GROUP 2 during the first three months, when GROUP 1 is in the intervention phase and GROUP 2 is in the non-intervention control phase.

Secondary Outcomes

  • Accelerometer-Based Physical Activity(6 months)
  • Late Life Function and Disability Scale, Frequency(6 months)
  • Late Life Function and Disability Scale, Limitation(6 months)

Study Sites (1)

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