Evaluation of Meibomian Gland Dysfunction in Chinese Old Patients

• Conditions: Dry Eye

• Registration Number: NCT02481167
• Lead Sponsor: Wenzhou Medical University

Brief Summary

The purpose of this study is to identify age-related changes in chinese meibomian glands that may be associated with meibomian gland dysfunction (MGD).

Detailed Description

Not available

Study Timeline

• Study Start: 2015-01
• Status Verified: 2015-06
• Study First Submitted: 2015-06-15
• Study First Submitted QC: 2015-06-24
• Last Update Submitted: 2015-06-24
• Study First Posted: 2015-06-25
• Last Update Posted: 2015-06-25
• Primary Completion: 2016-04
• Study Completion: 2018-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• have dry eye symptom
• have meibomian gland dysfunction

Exclusion Criteria

• diabetes
• history of ocular surgery
• systemic disease or inflammation

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The morphology of meibomian glands	1 year	The morphology of meibomian glands was evaluated by keratography
Tear film break-up time	1 year	Tear film break-up time (TBUT) was evaluated by placing a single fluorescein strip over the inferior tear meniscus after instilling a drop of normal saline.
Lower tear meniscus	1 year	Lower tear meniscus was evaluated by keratography

Trial Locations

Locations (1)

Wenzhou Medical University; 🇨🇳 Wenzhou, Zhejiang, China