Can intravenous lidocaine definitely attenuate propofol requirement and improve outcomes among colonoscopic patients under intravenous sedation?: A double-blinded, randomized controlled trial
Phase 4
Completed
- Conditions
- The propofol-sparing effect of intravenous lidocaine in patients undergoing colonoscopy with bispectral index monitoring.bispectral index, colonoscopy, lidocaine, monitoring, propofol
- Registration Number
- TCTR20210517001
- Lead Sponsor
- Phramongkutklao hospital
- Brief Summary
Intravenous lidocaine produced a definitely effective reduced propofol requirement without other sedative agents and improved outcomes including patient satisfaction, duration in returning to BIS more than 85, and sedation score during colonoscopy without adverse effects.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 68
Inclusion Criteria
1. Patients aged 20 to 80 years
2. American Society of Anesthesiologists physical status I-III
Exclusion Criteria
1. Severe cardiovascular and pulmonary diseases
2. Liver or renal insufficiency
3. Mental disorders
4. language barrier
5. history of colectomy
6. history of being allergic to lidocaine
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Total dosage of intravenous propofol At the end of the operation Milligram of propofol
- Secondary Outcome Measures
Name Time Method a comparison of hemodynamic variations, episodes of oxygen desaturation, the duration of full consciousness and prompt response to the PACU, the sedative level , patient satisfaction, pain score Within 60 minutes in the recovery room Verbal numerical rating score (VNRS), blood pressure and oxygen saturation percent changes, patient satisfaction, BIS