The Cardioprotective Effect of Intralipid in Decreasing the Ischemic Insults During Off-pump Coronary Artery Revascularization

Phase 4

Completed

• Conditions: Anesthesia
• Interventions: Drug: Placebo; Drug: Intralipid

• Registration Number: NCT04806425
• Lead Sponsor: Ain Shams University

Brief Summary

the aim of the study is to assess the effect of intralipid as regard efficiency in decreasing myocardial ischemia , given during preconditioning in off pump coronary artery revascularization

Detailed Description

Not available

Study Timeline

• Study Start: 2020-10-01
• Primary Completion: 2021-02-20
• Status Verified: 2021-03
• Study Completion: 2021-03-01
• Study First Submitted: 2021-03-17
• Study First Submitted QC: 2021-03-17
• Last Update Submitted: 2021-03-17
• Study First Posted: 2021-03-19
• Last Update Posted: 2021-03-19

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 46

Inclusion Criteria

• patients between 40 to 75 undergoing off bump CABG surgery

Exclusion Criteria

• emergency surgery
• Ejection fraction less than 50%
• redo procedures
• history of allergy to peanuts

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
NS group	Placebo	recieve 1.5 ml /kg normal saline 0.9% through central venous line after sternotomy over 1 hour
IL group	Intralipid	receive 1.5 ml /kg intralipid 20% through Central venous line after sternotomy over 1 hour

Primary Outcome Measures

Name	Time	Method
ICU stay	long icu stay is considered if more than 7 days	measuring the duration of stay in the ICU

Trial Locations

Locations (1)

Ain Shams University; 🇪🇬 Cairo, (Select), Egypt