Achilles tendon pain management (ATM): A study to evaluate an injection to improve pain in the Achilles tendo

Not Applicable

Completed

• Conditions: Achilles tendinopathy; Musculoskeletal Diseases; Achilles tendinitis

• Registration Number: ISRCTN13254422
• Lead Sponsor: niversity of Warwick

Brief Summary

2020 Protocol article in https://www.ncbi.nlm.nih.gov/pubmed/32051317 protocol (added 14/02/2020) 2021 Results article in https://pubmed.ncbi.nlm.nih.gov/34255009/ (added 14/07/2021)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2015-10-28
• Study Completion: 2020-09-29
• Last Update Posted: 20 November 2023

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 240

Inclusion Criteria

1. Provision of written informed consent
2. Aged 18 years or over
3. Pain at the mid-substance of the Achilles tendon for longer than 3 months
4. Ultrasound and/or MRI confirmation of tendinopathy

Exclusion Criteria

1. Presence of systemic conditions (including: diabetes, rheumatoid arthritis, peripheral vascular disease)
2. Pregnant or actively trying to become pregnant, or breastfeeding at the time of randomisation
3. Have had prior Achilles tendon surgery or rupture on the index side
4. Previous major tendon or ankle injury or deformity to either lower leg
5. Have had a fracture of a long bone in either lower limb in the previous 6 months
6. Have any contraindication to receiving a platelet rich plasma injection (haemodynamic instability, platelet dysfunction syndrome, cancer, septicaemia, systemic use of anticoagulant, local infection at site of the procedure)
7. Are unable to adhere to trial procedures or complete questionnaires
8. Previous randomisation in the present trial

Added 19/10/2016:
9. Previous PRP treatment into a tendon.

Study & Design

• Study Type: Interventional
• Study Design: Not specified