跳至主要内容
临床试验/CTRI/2024/04/065235
CTRI/2024/04/065235尚未招募不适用

Sankalp: Strengthening Program Implementation and Monitoring to Achieve Single-digit Neonatal Mortality

Indian Council of Medical Research10 个研究点 分布在 1 个国家目标入组 96,000 人开始时间: 2024年4月25日最近更新:

试验速览

阶段
不适用
状态
尚未招募
入组人数
96,000
试验地点
10
主要终点
Neonatal mortality rate

研究概览

简要总结

Background & rationale: While India has made significant strides in reducing child mortality, nearly 5 lakh newborns continue to die each year, mostly due to preventable causes. Further, newborn survival is a field with a well-established evidence base of impactful interventions that have also been integrated into the national policy, but with persistent challenges in last-mile delivery. This “know-do” gap between evidence-based practices and how to implement them to achieve high coverage and quality at scale can be bridged through implementation research (IR) in close partnership with the health system. There are wide inter-state, inter-district, and potentially even intra-district variations in the neonatal mortality rate (NMR). Prematurity, birth asphyxia and infections are the main causes of neonatal deaths, but their relative distribution may vary with the NMR and local context across regions. Therefore, this multi-state multi-district IR study has been designed to develop effective implementation strategies for a package of evidence-based interventions that are contextualized to different state/regional contexts with the goal of achieving single-digit NMR in each study district.

**Research question:**How to achieve a single-digit neonatal mortality rate (NMR) in selected high-NMR districts of India by developing and optimizing an implementation model for delivering evidence-based practices to pregnant women and newborns?

Objectives:

1. To co-develop and optimize context-specific/ contextualized implementation strategies for achieving high and equitable coverage and quality of evidence-based practices (EBP) for reducing neonatal mortality.

2. To document the process of evolution (adaptation and fidelity) of the implementation model.

3. To evaluate the effect of the optimized and contextualized implementation model on the neonatal mortality rate.

研究设计

研究类型
Interventional
分配方式
Na
盲法
None

入排标准

年龄范围
0.00 Day(s) 至 28.00 Day(s)(—)
性别
All

入选标准

  • 未提供

排除标准

  • Refusal for consent.

结局指标

主要结局

Neonatal mortality rate

时间窗: Outcome will be studied at various time points in the form of an interrupted time series.

次要结局

  • 1. Perinatal mortality rate(2. Proportion of newborns who were provided early (within one hour) & exclusive breastfeeding)

研究者

申办方类型
Government funding agency
责任方
Principal Investigator
主要研究者

Dr Amlin Shukla (Study Coordinator)

Indian Council of Medical Resarch

研究点 (10)

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