The Effect of Local Vibration Applied to Spastic Gastrocnemius on Muscle Architecture and Functional Properties in Multiple Sclerosis Patients
Trial Snapshot
- Phase
- Not Applicable
- Sponsor
- Hacettepe University
- Enrollment
- 30
- Locations
- 1
- Primary Endpoint
- Evaluation of Muscle Thickness and Fascicle Length with Ultrasonography
Study Overview
Brief Summary
Gastrocnemius spasticity is one of the main complaints in Multiple Sclerosis patients.Local muscle vibration is a method used for spasticity inhibition. However, when the studies in the literature are examined; It is noted that local vibration applications for spasticity are usually single sessions and evaluate the acute effect, do not produce functional outputs, there is no consensus on frequency and amplitude and the changes in muscle architecture are not examined. In this study, we aimed to investigate the effect of local vibration applied on spastic gastrocnemius on muscle architectural and functional properties in Multiple Sclerosis patients in addition to the standard physiotherapy program. The study was planned to include 3 groups, 2 treatment and 1 control group. The control group will receive standard physiotherapy, one of the treatment groups will receive 50 Hz local vibration in addition to standard physiotherapy, and other treatment group will receive 100 Hz local vibration in addition to standard physiotherapy. Disease severity, gastrocnemius spasticity, architectural and viscoelastic properties of muscle, ankle proprioception, balance and gait skills will be evaluated before and after 8 weeks treatment program. As a result; effectiveness of local vibration in addition to standard physiotherapy program and whether there is a difference between applications at different frequencies will be examined.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- Single (Outcomes Assessor)
Eligibility Criteria
- Ages
- 18 Years to 65 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •> 18 years
- •EDSS<5,5
- •Gastrocnemius spasticity<2
Exclusion Criteria
- •having any injury or surgery of the lower extremity
- •having systemic and metabolic disease
- •having behavioral and cognitive problems that prevent consistence to guidelines given
Arms & Interventions
Treatment Group 50 Hz
Intervention: Standard physiotherapy program+50 Hz local vibration (Other)
Treatment Group 100 Hz
Intervention: Standard physiotherapy program+100 Hz local vibration (Other)
Control Group
Intervention: Standard physiotherapy program (Other)
Outcomes
Primary Outcomes
Evaluation of Muscle Thickness and Fascicle Length with Ultrasonography
Time Frame: 3 minutes
Bilateral Medial Gastrocnemius US evaluations were performed with use of a 5-10 MHz linear probe (Diasus Dynamic Imaging Ltd, Livingston, Scotland,UK). Patients were positioned prone position with their legs and their muscles relaxed for medial gastrocnemius. Muscle Thickness and Fascicle Length would be expressed as centimeters.
Evaluation of Pennation Angle with Ultrasonography
Time Frame: 2 minutes
Bilateral Medial Gastrocnemius US evaluations were performed with use of a 5-10 MHz linear probe (Diasus Dynamic Imaging Ltd, Livingston, Scotland,UK). Patients were positioned prone position with their legs and their muscles relaxed for medial gastrocnemius. Pennation Angle would be angularly indicated.
Secondary Outcomes
- Assessment of gait characterictics(5 minutes)
- Assessment of single leg balance(3 minutes)
- Assessment of balance(10 minutes)
- Assessment of spasticity(5 minutes)
- Assessment of viscoelastic properties of muscle(5 minutes)
- Assessment of ankle proprioception(5 minutes)
Investigators
Fatma Ayvat
Research Assistant
Hacettepe University