Change in carotid corrected flow time induced by recruitment maneuver as a predictor of fluid responsiveness

Not Applicable

• Conditions: Patients undergoing general anesthesia

• Registration Number: JPRN-UMIN000036548
• Lead Sponsor: Department of Anesthesiology, Osaka City University Graduate School of Medicine

Brief Summary

Twenty patients (67%) were fluid responders. All Doppler images for carotid flow time were obtained within 30s. Changes in the corrected flow time accurately predicted fluid responsiveness (area under the curve: 0.82, 95% CI 0.64-0.94, p=0.002). The optimal threshold for changes in the corrected flow time was -11.7% with a sensitivity of 95.0% (95% CI 75.1-99.9%) and a specificity of 80.0% (95% CI 44.4-97.5%).

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-04-20
• Study Completion: 2019-11-30
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Complete: follow-up complete
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

Not provided

Exclusion Criteria

1. Atrial fibrillation, atrial flutter 2. Cerebral vascular disease 3. Decreased cardiac function (NYHA classification: 3 or more than 3, valve regurgitation: moderate or severe, ejection fraction <50%) 4. Decreased renal function (eGFR < 30mL/min/1.73m2) 5. Decreased respiratory function (%FEV1.0<70% and %VC<70%)

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Changes in stroke volume after volume expansion

Secondary Outcome Measures

Name	Time	Method
Changes in arterial pressure after volume expansion