Endovascular treatmenT for Acute Ischemic Stroke in China

Completed

• Conditions: Endovascular Treatment; Stroke

• Registration Number: NCT04752735
• Lead Sponsor: General Hospital of Shenyang Military Region

Brief Summary

This is a retrospective real world registry study, aiming to explore the effectiveness and safety of endovascular treatment of acute ischemic stroke in a Chinese population.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2021-02-10
• Study First Submitted QC: 2021-02-10
• Study First Posted: 2021-02-12
• Study Start: 2021-03-22
• Status Verified: 2023-02
• Primary Completion: 2023-02-08
• Study Completion: 2023-02-08
• Last Update Submitted: 2023-02-08
• Last Update Posted: 2023-02-10

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 1000

Inclusion Criteria

• Age: ≥ 18;
• Ischemic stroke confirmed by head CT or MRI;
• Patients receiving endovascular treatment;
• First ever stroke or mRS≤2 after previous disease;
• Complete and clear pre- and post-operative DSA images are available

Exclusion Criteria

• Imaging data not qualified for evaluation;
• Absence of important clinical data;
• The first 50 patients receiving endovascular treatment in a single centerr.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Proportion of patients with modified Rankin Score (mRS) 0 to 2	Day 90	the minimum and maximum values of mRS are 0 and 6, respectively; higher mRS mean a worse outcome

Secondary Outcome Measures

Name	Time	Method
Proportion of intraparenchymal hemorrhage (PH1 and PH2)	48 hours	Proportion of intraparenchymal hemorrhage (PH1 and PH2) after treatment
Proportion of patients with modified Rankin Score 0 to 2	Day180, 360	Proportion of patients with modified Rankin Score 0 to 2
Proportion of symptomatic intracranial hemorrhage (sICH)	48 hours	sICH was defined as 4 or more increase in NIHSS caused by hemorrhage
Proportion of death	Day 7	death due to any cause
Changes in National Institute of Health stroke scale (NIHSS)	Day 2, 7, 14	the minimum and maximum values of NIHSS are 0 and 42, respectively; higher NIHSS mean a worse outcome
Distribution of modified Rankin Score	Day 90, 180, 360	Distribution of modified Rankin Score after treatment
Changes in cerebral edema	48 hours, 7 days	edema is determined by middle shift.

Trial Locations

Locations (1)

Department of Neurology, General Hospital of Northern Theater Command; 🇨🇳 Shenyang, China