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Clinical Trials/NCT04752735
NCT04752735
Completed
Not Applicable

Endovascular treatmenT for Acute Ischemic Stroke in China: a Retrospective, National, Multi-center, Registry Study

General Hospital of Shenyang Military Region1 site in 1 country1,000 target enrollmentMarch 22, 2021

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Stroke
Sponsor
General Hospital of Shenyang Military Region
Enrollment
1000
Locations
1
Primary Endpoint
Proportion of patients with modified Rankin Score (mRS) 0 to 2
Status
Completed
Last Updated
3 years ago

Overview

Brief Summary

This is a retrospective real world registry study, aiming to explore the effectiveness and safety of endovascular treatment of acute ischemic stroke in a Chinese population.

Registry
clinicaltrials.gov
Start Date
March 22, 2021
End Date
February 8, 2023
Last Updated
3 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
General Hospital of Shenyang Military Region
Responsible Party
Principal Investigator
Principal Investigator

Hui-Sheng Chen

Head of Neurology

General Hospital of Shenyang Military Region

Eligibility Criteria

Inclusion Criteria

  • Age: ≥ 18;
  • Ischemic stroke confirmed by head CT or MRI;
  • Patients receiving endovascular treatment;
  • First ever stroke or mRS≤2 after previous disease;
  • Complete and clear pre- and post-operative DSA images are available

Exclusion Criteria

  • Imaging data not qualified for evaluation;
  • Absence of important clinical data;
  • The first 50 patients receiving endovascular treatment in a single centerr.

Outcomes

Primary Outcomes

Proportion of patients with modified Rankin Score (mRS) 0 to 2

Time Frame: Day 90

the minimum and maximum values of mRS are 0 and 6, respectively; higher mRS mean a worse outcome

Secondary Outcomes

  • Proportion of intraparenchymal hemorrhage (PH1 and PH2)(48 hours)
  • Proportion of patients with modified Rankin Score 0 to 2(Day180, 360)
  • Proportion of symptomatic intracranial hemorrhage (sICH)(48 hours)
  • Changes in National Institute of Health stroke scale (NIHSS)(Day 2, 7, 14)
  • Distribution of modified Rankin Score(Day 90, 180, 360)
  • Proportion of death(Day 7)
  • Changes in cerebral edema(48 hours, 7 days)

Study Sites (1)

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