Internet-based Cognitive Behavior Therapy (CBT) for Obsessive Compulsive Disorder (OCD)

Phase 2

Completed

• Conditions: Obsessive Compulsive Disorder
• Interventions: Behavioral: Support therapy on Internet; Behavioral: Internet-based cognitive behavior therapy

• Registration Number: NCT01347099
• Lead Sponsor: Karolinska Institutet

Brief Summary

Cognitive behavior therapy (CBT) is an effective treatment for obsessive compulsive disorder (OCD) but there is a lack of properly trained CBT therapists. One possible treatment alternative is Internet-based CBT (ICBT) with minimal therapist input. The aim of this study was therefore to evaluate ICBT for OCD.

Detailed Description

This is a randomized controlled trial with 101 participants. The control group receives support therapy on demand on the Internet.

Study Timeline

• Study Start: 2011-02
• Status Verified: 2011-05
• Study First Submitted: 2011-05-02
• Study First Submitted QC: 2011-05-03
• Study First Posted: 2011-05-04
• Primary Completion: 2011-06
• Study Completion: 2011-06
• Last Update Submitted: 2018-03-19
• Last Update Posted: 2018-03-21

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 101

Inclusion Criteria

• Primary diagnosis of obsessive compulsive disorder (OCD)
• At least 18 years old
• Able to read and write in swedish
• Computer access

Exclusion Criteria

• other primary diagnosis
• substance abuse,
• psychosis,
• bipolar disorder,
• suicidal ideation,
• adjusted pharmacological treatment the last two months
• current psychological treatment for OCD,
• been treated with CBT the last two years,
• serious somatic disease,
• Y---BOCS>31
• hoarding as primary OCD subtype

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Support therapy	Support therapy on Internet	10 weeks. Therapist support contact through e-mail.
Internet CBT	Internet-based cognitive behavior therapy	Internet-delivered CBT. Contact with therapist thru an e-mail system. 10 weeks.

Primary Outcome Measures

Name	Time	Method
Change from Baseline of obsessions and compulsions after 10 weeks and at 3- and 12 months after treatment.	Two weeks before treatment, 10 weeks after treatment starts, 3 and 12 months after treatment has ended	Yale Brown Obsessive Compulsive Scale (Y-BOCS)

Secondary Outcome Measures

Name	Time	Method
Change from Baseline of quality of life after 10 weeks and at 3- and 12 months after treatment.	Two weeks before treatment, 10 weeks after treatment starts, 3 and 12 months after treatment has ended	Euroqol
Change from Baseline of depressive symptoms after 10 weeks and at 3- and 12 months after treatment.	Two weeks before treatment, 10 weeks after treatment starts, 3 and 12 months after treatment has ended	Montgomery Asberg Depression Rating Scale
Change from Baseline of obsessions and compulsions after 10 weeks and at 3- and 12 months after treatment.	Two weeks before treatment, 10 weeks after treatment starts, 3 and 12 months after the treatment has ended	Dimensional Obsessive Compulsive Scale (DOCS)
Change from Baseline of meta cognitions after 10 weeks and at 3- and 12 months after treatment.	Two weeks before treatment, 10 weeks after treatment starts, 3 and 12 months after treatment has ended	Obsessive Beliefs Scale

Trial Locations

Locations (1)

Psykiatri Sydväst; 🇸🇪 Stockholm, Sweden