Internet-based Cognitive Behavior Therapy for Obsessive Compulsive Disorder: A Randomized Controlled Trial
Trial Snapshot
- Phase
- Phase 2
- Status
- Completed
- Sponsor
- Karolinska Institutet
- Enrollment
- 101
- Locations
- 1
- Primary Endpoint
- Change from Baseline of obsessions and compulsions after 10 weeks and at 3- and 12 months after treatment.
Study Overview
Brief Summary
Cognitive behavior therapy (CBT) is an effective treatment for obsessive compulsive disorder (OCD) but there is a lack of properly trained CBT therapists. One possible treatment alternative is Internet-based CBT (ICBT) with minimal therapist input. The aim of this study was therefore to evaluate ICBT for OCD.
Detailed Description
This is a randomized controlled trial with 101 participants. The control group receives support therapy on demand on the Internet.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- Single (Outcomes Assessor)
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Primary diagnosis of obsessive compulsive disorder (OCD)
- •At least 18 years old
- •Able to read and write in swedish
- •Computer access
Exclusion Criteria
- •other primary diagnosis
- •substance abuse,
- •psychosis,
- •bipolar disorder,
- •suicidal ideation,
- •adjusted pharmacological treatment the last two months
- •current psychological treatment for OCD,
- •been treated with CBT the last two years,
- •serious somatic disease,
- •Y---BOCS>31
- •hoarding as primary OCD subtype
Arms & Interventions
Internet CBT
Internet-delivered CBT. Contact with therapist thru an e-mail system. 10 weeks.
Intervention: Internet-based cognitive behavior therapy (Behavioral)
Support therapy
10 weeks. Therapist support contact through e-mail.
Intervention: Support therapy on Internet (Behavioral)
Outcomes
Primary Outcomes
Change from Baseline of obsessions and compulsions after 10 weeks and at 3- and 12 months after treatment.
Time Frame: Two weeks before treatment, 10 weeks after treatment starts, 3 and 12 months after treatment has ended
Yale Brown Obsessive Compulsive Scale (Y-BOCS)
Secondary Outcomes
- Change from Baseline of quality of life after 10 weeks and at 3- and 12 months after treatment.(Two weeks before treatment, 10 weeks after treatment starts, 3 and 12 months after treatment has ended)
- Change from Baseline of depressive symptoms after 10 weeks and at 3- and 12 months after treatment.(Two weeks before treatment, 10 weeks after treatment starts, 3 and 12 months after treatment has ended)
- Change from Baseline of obsessions and compulsions after 10 weeks and at 3- and 12 months after treatment.(Two weeks before treatment, 10 weeks after treatment starts, 3 and 12 months after the treatment has ended)
- Change from Baseline of meta cognitions after 10 weeks and at 3- and 12 months after treatment.(Two weeks before treatment, 10 weeks after treatment starts, 3 and 12 months after treatment has ended)
- Change from Baseline of obsessions and compulsions after 10 weeks and at 3- and 12 months after treatment.(Two days before treatment, once per week for 10 weeks after treatment starts, 3 and 12 months after treatment has ended)