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Clinical Trials/ACTRN12612001040853
ACTRN12612001040853
Completed
Phase 1

The effects of pulsatile, when compared to continuous, infusion of glucagon-like peptide-1 on insulin secretion and blood glucose in healthy humans

Royal Adelaide Hospital Intensive Care Unit0 sites12 target enrollmentSeptember 28, 2012
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Overview

Phase
Phase 1
Intervention
Not specified
Conditions
Not specified
Sponsor
Royal Adelaide Hospital Intensive Care Unit
Enrollment
12
Status
Completed
Last Updated
6 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
September 28, 2012
End Date
TBD
Last Updated
6 years ago
Study Type
Interventional
Sex
All

Investigators

Sponsor
Royal Adelaide Hospital Intensive Care Unit

Eligibility Criteria

Inclusion Criteria

  • •Healthy volunteers able to give informed consent

Exclusion Criteria

  • •Inability to give informed consent
  • •History of diabetes
  • •Women who are pregnant or lactating
  • •History of pancreatitis
  • •Haemoglobin \<125g/L for women and \<135g/L for men
  • •Glycated haemoglobin (HbA1c) \>6\.0 %
  • •Ferritin levels for women \<10microgram/L and \<20microgram/L for men
  • •Estimated glomerular filtration rate \< 60ml/min
  • •Impaired liver function (ALT: \>55 U/L; Albumin: \<34g/l; ALP: \>110 U/L; Bilirubin: \>25 micro mol; GGT: \>80U/L)
  • •Blood donation within the previous 12 weeks

Outcomes

Primary Outcomes

Not specified

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