Feasibility and repeatability of an incremental exercise test on the combined arm-leg (Cruiser) ergometer in patients with a lower limb amputatio

Completed

Conditions: 10003216
amputation of the lower limb
lower limb amputation
10005942
10005959

Registration Number: NL-OMON37936

Lead Sponsor: niversitair Medisch Centrum Groningen

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: Not specified

Target Recruitment: 30

Inclusion Criteria

Patients with a lower limb amputation (unilateral transfemoral amputation, knee disarticulation or transtibial amputation).

Exclusion Criteria

The subjects will be excluded from this study if there is evidence or serious suspicion of coronary disease, stress or exercise related pain in the chest, untreated symptomatic arrhythmia*s (ventricular tachycardia or any rhythm significantly compromising cardiac function), hypertension with a diastolic bloodpressure of > 100 mm Hg or systolic bloodpressure > 180 mm Hg, acute pulmonary embolus, bilateral lower limb amputations or upper limb amputation, mental impairment leading to inability to cooperate or inability to obtain consent

Study & Design

Study Type: Observational non invasive

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Maximal oxygen uptake (VO2max in l/min)</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Gross Efficiency (% of external work performed to the total production of<br /><br>energy), metabolic equivalent of exercising (MET in 3.5 ml O2 /kg/min),<br /><br>maximal carbon dioxide output (VCO2 in liters per minute), heart rate (HR in<br /><br>beats per minute), maximal workload (W),blood pressure (BP in mmHg), breathing<br /><br>frequency (BF in breaths per minute) maximal ventilation (VE liters per<br /><br>minute), respiratory exchange rate (RER in %) and rate of perceiverd exertion<br /><br>(RPE in 10 point borg-scale)</p><br>