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Clinical Trials/NCT07655986
NCT07655986RecruitingNot Applicable

Impact of a High-resolution Program for the Prevention of Suicidal Behavior in At-risk Adults: a Quasi-experimental Ambispective Cohort Study

University of Salamanca1 site in 1 country198 target enrollmentStarted: May 1, 2025Last updated:

Trial Snapshot

Phase
Not Applicable
Status
Recruiting
Enrollment
198
Locations
1

Study Overview

Brief Summary

Background: Suicidal behavior represents a major public health problem worldwide. According to the World Health Organization (WHO), approximately 720.000 people die by suicide annually, and many more attempt it. Suicide is a personal tragedy associated with extreme suffering that has a serious impact on the deceased's immediate circle and on society as a whole. In this context, there is an urgent need to design effective and humane intervention strategies that offer an evidence-based, preventive, specialized, and community-oriented response to suicidal behavior.

Objective: To evaluate the impact of a multidisciplinary, specialized, and high-resolution program for the prevention of suicidal behavior in adults aged 18 and over in the Salamanca Health Area.

Methods: A quasi-experimental, ambispective cohort study with two parallel groups: an intervention group, receiving the specific suicide prevention program (SPP) with a pre-test/post-test design, and a control group, receiving usual care (TC). Adult patients (≥ 18 years) will be referred from the Emergency Department of the University Hospital of Salamanca after an initial psychiatric evaluation. Patients will be assigned to the intervention group according to established inclusion criteria. The program lasts 3 months, during which each participant will receive intensive and individualized follow-up from a multidisciplinary team composed of two psychiatrists, two mental health nurses, two psychologists, and two social workers at two community mental health centers. Participants will also attend 10 weekly group therapy sessions. Follow-up evaluations will be conducted at the end of the program (three months) and six months after the first contact.

Discussion: This study will contribute to the scientific evidence base on the effectiveness of intensive and specific suicide prevention programs in the community setting, optimizing healthcare resources, improving treatment adherence, and aligning with the Spanish National Suicide Prevention Plan 2025-2027. Ethics and dissemination: This study has been approved by the Clinical Research Ethics Committee of the Salamanca Health Area (CEIm code: PI 2025 11 2102 - TD)

Keywords: Suicidal behavior; Suicide prevention; Suicidal ideation; Community mental health services; Quasi-experimental study; Cohort study; Psychiatric emergency services; Patient care team.

Detailed Description

INTRODUCTION.

Epidemiological and Clinical Impact of Suicidal Behavior. Suicidal behavior is a phenomenon of increasing impact and one of the main public health concerns globally. According to the most recent data from the World Health Organization (WHO), published in 2025, more than 720,000 people die by suicide each year worldwide, a figure far exceeded by the number of attempts. It is estimated that for every completed suicide, there are approximately 20 attempts, and this is why these prior suicidal behaviors are consolidated as the individual risk factor with the greatest predictive value for future episodes. Suicidal behaviors generate extreme suffering with profound repercussions for both the individual and their socio-familial environment, thus generating a health and social impact of great magnitude. This is why suicide prevention has currently become a strategic priority on public health agendas.

In Spain, according to the latest data from the National Institute of Statistics (INE), there were 4,116 deaths by suicide in 2023, making it the second leading cause of death from external causes. The crude rate is 8.5 suicides per 100,000 inhabitants, with a notably asymmetrical distribution between sexes: 74% of cases correspond to men and 26% to women. These figures translate to an average of ten people committing suicide in Spain every day, highlighting the urgent need for effective clinical and preventative interventions.

Regulatory and strategic framework. The prevention of suicidal behavior is based on a solidly defined international and national strategic framework. Globally, the WHO's Action Plan for Suicide Prevention 2013-2030 establishes, in its third objective, the imperative need to implement mental health promotion and prevention strategies throughout the life cycle, with a commitment to reducing the suicide rate by one-third by 2030. In the Spanish context, the National Health System's (SNS) Mental Health Strategy 2022-2026 prioritizes, in its third strategic line, strengthening prevention, early detection, and optimizing the quality of care in this area. These guidelines are reinforced by the SNS's specific Action Plan for Suicide Prevention 2025-2027, which intensifies these measures with special emphasis on the most vulnerable groups and promotes intersectoral coordination as a response from the healthcare system.

Under this paradigm, the need arises to design effective and humanized intervention strategies as a comprehensive response, offering an effective response to the problem of suicide from a preventive, specialized, and community-based approach. Suicidal behavior is a preventable phenomenon through systematic and multidisciplinary actions.

Study Design

Study Type
Interventional
Allocation
Non Randomized
Intervention Model
Parallel
Primary Purpose
Prevention
Masking
None

Eligibility Criteria

Ages
18 Years to — (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • Patients ≥ 18 years of age.
  • No prior active follow-up by the mental health team.
  • Prior stabilization by the emergency psychiatry team.
  • Columbia Severity Rating Scale (C-SSRS) score corresponding to moderate-to-high risk.
  • Absence of criteria for urgent hospital admission.
  • Signed informed consent.
  • Exclusión Criteria:
  • Self-harm without suicidal intent.
  • Mild suicide risk (mild C-SSRS).
  • Extremely high suicide risk requiring urgent hospital admission.
  • Patient under active follow-up at another mental health unit.

Exclusion Criteria

  • Not provided

Investigators

Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

MARÍA DE LA LUZ SÁNCHEZ TOCINO

Associate professor doctor, University of Salamanca

University of Salamanca

Study Sites (1)

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