EUCTR2015-002202-37-NL进行中（未招募）不适用
Pilot study: Is concomitant administration of lidocaine during oxaliplatin infusion able to prevent pain as a result of oxaliplatin induced acute neuropathy? - LiO
适应症
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 发起方
- radboudumc
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •Subjects with stage II to IV colorectal adenocarcinoma, who are scheduled to receive 6-8 cycles of oxaliplatin 130 mg/m2 every 3 weeks .
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range 16
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range 8
排除标准
- •Receiving other chemotherapeutics in medical history
- •Allergy to amide type of local anesthetics
- •Recent myocardial ischemia (<6 months)
- •Renal function disorders (MDRD < 60)
- •Liver failure (bilirubine > 1,5x upper limit of normal)
- •Adequate hematologic parameters
- •Hypokaliemia
- •Pregnancy or lactating
- •Use of anti-arythmic drugs (flecainide)
- •Pre-existing form of neuropathy (polyneuropathy or small fibre neuropathy)
- •History of chronic pain and opioid use
- •Risk factors for CIPN: alcoholism, diabetes mellitus
- •No written informed consent by patient
研究者
相似试验
招募中
4 期
Pilot study: Is concomitant administration of lidocaine during oxaliplatin infusion able to prevent pain as a result of oxaliplatin induced acute neuropathy?PijngeneeskundeOxaliplatin induced nerve pain10017991NL-OMON42676Academisch Medisch Centrum24
已完成
不适用
Effect of lidocaine injection on postoperative pain of cataract surgeryCataract.Senile cataract and other cataractH25 ,H26IRCT2014072518589N1Vice chancellor For Research Of Ahvaz Jondishapour University of Medical Sciences48
进行中（未招募）
1 期
Study on the efficacy and safety of lidocaine tape application as a surface anesthesia for the mucous membranes of the mouthHealthy volunteersJPRN-jRCTs061230003Yanamoto Souichi14
已完成
不适用
To investigate the efficacy and safety of lenalidomide and dexamethasone for elderly or frail patients with relapsed/refractory multiple myelomaMultiple MyelomaJPRN-UMIN000008576Iwate Myeloma treatment Study Group53
已完成
不适用
Efficacy and safety of combination therapy of vildagliptin and insuliType 2 diabetes mellitusJPRN-UMIN000011828Department of Internal Medicine, School of Medicine, Keio University40