跳至主要内容
临床试验/NCT05634733
NCT05634733招募中不适用

Evaluation of Mitral Annulus Systolic Plane Excursion (MAPSE) in Emergency Department Patients With Sepsis

University of Maryland, Baltimore1 个研究点 分布在 1 个国家目标入组 50 人开始时间: 2023年4月1日最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
入组人数
50
试验地点
1
主要终点
Change in MAPSE measurement

研究概览

简要总结

Patients with bloodstream infections (sepsis) have been found in prior studies to have infection-related heart dysfunction, even if they did not have preexisting heart problems. Factors related to the infection may cause the heart to not pump as well as it should, causing critical illness in the form of low blood pressure (shock) and heart failure. Ultrasound is frequently used in the emergency department to evaluate why a patient might have low blood pressure. Part of that evaluation may include obtaining ultrasound images and making measurements about how well or poorly the heart is pumping. The investigators will evaluate a certain measurement that relates to cardiac function, determine how it changes in patients before and after they are treated for septic shock. This will involve placing an ultrasound probe on the patient's chest, measuring the upward and downward movement of the mitral valve, the mitral annulus systolic plane excursion (MAPSE), and comparing the measurements before and after treatment is started. The investigators are attempting to determine if this measurement improves before and after treatment.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Diagnosis of Sepsis or Septic Shock

排除标准

  • Age equal to or less than 17
  • patient in the emergency department
  • Unable to perform POCUS exam due to medical necessity
  • Patients without sepsis
  • unable to obtain consent or have a legal representative consent

结局指标

主要结局

Change in MAPSE measurement

时间窗: 1 hour after treatment initiation

Does the MAPSE change after treatment of MAPSE

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Alexis Salerno

Assistant Professor of Emergency Medicine

University of Maryland, Baltimore

研究点 (1)

Loading locations...

相似试验