Effectiveness of intrauterine Growth Hormone administration as an add-on therapy to conventional hormone therapy compared to placebo in patients with thin endometrium undergoing frozen thawed embryo transfer
Phase 3
Recruiting
- Conditions
- Infertility.Female Infertility
- Registration Number
- IRCT20110908007513N18
- Lead Sponsor
- Esfahan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Female
- Target Recruitment
- 54
Inclusion Criteria
Have at least a history of cycle cancellation due to a thin endometrium less than 7 mm following standard hormonal treatment
Age 18-45 years
Availability of =1 embryo with good quality
Normal baseline hormones value including : Testosterone, Progesterone, Prolactin, LH, FSH
Exclusion Criteria
Internal genital anomalies
Active intrauterine infection
ET=7 on the 10th day of cycle
History of Asherman syndrome
History of cancer
History of uterine surgery in past 3 months
Intrauterine polyps visible in Transvaginal Ultrasonography
Visible intrauterine adhesion
Pathospermia in partner
Premature ovarian failure
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Endometrial thickness. Timepoint: Baseline (10th day of cycle), and On the day of response to treatment (in case of response) and in case of non-response to treatment on the 18th day of the cycle. Method of measurement: Transvaginal ultrasonography.
- Secondary Outcome Measures
Name Time Method