Clinical outcomes of Mucormycosis

Not yet recruiting

• Conditions: Other specified viral infections characterized by skin and mucous membrane lesions,

• Registration Number: CTRI/2023/05/052614
• Lead Sponsor: NA

Brief Summary

**BACKGROUND-**

Mucormycosis (formerly known as zygomycosis) is an uncommon, opportunistic fungal infection primarily caused by Mucorales, a filamentous fungus of the Mucormycetes class. Mucormycosis is a rare but devastating fungal infection primarily affecting immunocompromised patients such as those with hematological malignancy, bone marrow and solid organ transplantation, and patients with diabetes, and, even more rarely, immune competent patients.

(**Dimitrios P. Kontoyiannis2016** )

Mucormycosis is an angiovasive infection caused by the ubiquitous filamentous fungi of the  order Mucorales and class of  Mucormycetes. Mucormycosis is emerging infection in COVID 19 Pandemic Era**.(George Petrikkos, Anna Skiad 2021)**

Thus all review and studies supported tha mucormycosis is a very dangerous infection among the patient with history of COVID19,DM, Immunocompromised condition .All these studies show many clinical outcomes in forms of disturbances among the patients  inspite of taking treatment. Mucormycosis is emerging health issue as in COVID 19 Pandemic era so it is important to conduct the research study on this problem . In India there are very less no of research studies conducted on such emerging problem.

**PURPOSE OF STUDY** –

The  Study aims to investigate the clinical feature of mucormycosis, History of  COVID 19 and specific system disorder and treatment outcome of admitted patients . This will help in find out  the association of contributing factors and clinical outcome of patient as  well as development of intervention  according the need of patient .

The study also  aims to assess the prospective clinical outcome in form of physical , psychological and social  status  among patients admitted for    treatment of mucormycosis  .These outcomes will helpful in development of intervention of physical, psychological and social dimension  of care of patient with mucormycosis.

Detailed Description

Not available

Study Timeline

• Study Start: 2023-05-17
• Last Update Posted: 2023-12-05

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 10

Inclusion Criteria

• For Qualitative Study sample will selected for study who full fill following criteria Biopsy Proved Mucormycosis patient.
• Patient who are admitted at RUHS College of Dental Science Jaipur Patient with or without history of COVID 19 .
• Patient who will admitted at the time of data collection.
• Or discharged from hospital within 3 days or near about to discharge.
• Patient who respond to question during collection of qualitative data.
• If Patient unable to respond due to surgical procedure then get information from care giver.

Exclusion Criteria

• For Qualitative study patient will excluded from study- Patient who discharged from hospital and more than 3 days.
• Patient have another Oral cavity complication from long time before getting mucormycosis infection.Patient who not willing to participate study.
• Patient with Mucormycosis involed other than Orofacial area.
• Children are excluded.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To explore the experiences regarding clinical outcome in terms of physical, social and psychological disturbances among the patients with mucormycosis.	6 MONTHS

Secondary Outcome Measures

Name	Time	Method
find out the association between mucormycosis and selected variables (age, gender, COVID -19 ) among the patients with mucormycosis.	6 Months

Trial Locations

Locations (1)

RUHS COLLEGE OF DENTAL SCIENCES AND HOSPITAL, JAIPUR (RAJASTHAN)R d; 🇮🇳 Jaipur, RAJASTHAN, India

RUHS COLLEGE OF DENTAL SCIENCES AND HOSPITAL, JAIPUR (RAJASTHAN)R d

🇮🇳Jaipur, RAJASTHAN, India

VIRENDRA SINGH

Principal investigator

9460103856

Singhvirendra809@gmail.com