CoDeLaGe A translational cohort study on self-injurious behaviour in people with Cornelia de Lange Syndrome

Completed

• Conditions: self-destructive behavior; self-injurious behavior; 10027664; 10042460

• Registration Number: NL-OMON44024
• Lead Sponsor: Academisch Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 29 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 65

Inclusion Criteria

People with CdLS
1-molecularly confirmed
2-defined by clinical criteria and molecularly analysed for the known mutations, but not (yet) confirmed

Exclusion Criteria

People with CdLS with parents or caregivers who are insufficiently fluent in Dutch to understand sufficiently information letters and questionnaires.

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>-genetic profile by molecular gene analysis<br /><br>-behavioural and neuropsychological phenotype with respect to SIB<br /><br>-physical phenotype with respect to SIB<br /><br>-severity scores with respect to SIB</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Correlation between the above mentioned primary characteristics.</p><br>