Comparative Evaluation of Analgesic Outcomes of Intra-peritoneal Versus Subcutaneous Infiltration of Bupivacaine for Laparoscopic Cholecystectomy Patients "
Overview
- Phase
- Phase 4
- Status
- Recruiting
- Sponsor
- Rawalpindi Medical College
- Enrollment
- 100
- Locations
- 1
- Primary Endpoint
- Post opestive pain score
Overview
Brief Summary
Laparoscopic cholecystectomy involves removal of gallbladder through small incision ports resulting in faster recovery. Small incisions are less painful and hence local anesthesis administered can be effective for pain management. This local anesthetic can be administered either within abdominal cavity or at sit of small incisions.
Detailed Description
Laparoscopic cholecystectomy is a minimally invasive surgical procedure involving removal of the gallbladder through multiple small trocar incisions. Compared with open surgery, this approach is associated with reduced postoperative pain, shorter hospital stay, and faster recovery. Despite its minimally invasive nature, postoperative pain remains a significant concern, particularly at port sites and from intraperitoneal irritation. Local anesthetic techniques have been shown to contribute to multimodal analgesia in laparoscopic surgery. Local anesthetic agents may be administered either intraperitoneally or by infiltration at trocar insertion sites to reduce postoperative pain and opioid requirements. However, the optimal route of local anesthetic administration for effective postoperative analgesia following laparoscopic cholecystectomy remains uncertain, warranting further clinical evaluation.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- Double (Participant, Outcomes Assessor)
Eligibility Criteria
- Ages
- 15 Years to 60 Years (Child, Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •ASA I and II
Exclusion Criteria
- •Allergic to local anesthetic Open cholecystectomy History of chronic pain History of abdominal surgery
Arms & Interventions
Intraperitoneal local anesthetic administration
Intervention: Intraoperitoneal local anesthetic administration (Drug)
Sub cutaneous local anesthetic administration
Intervention: Sub cutaneous administration of local anesthetic (Drug)
Outcomes
Primary Outcomes
Post opestive pain score
Time Frame: This will be measured using Visual Analog score upon arrival at post anesthesia care unit labelled as Time 0 then at time intervals 3h,6h, 12h and 24 hours post operatively
Rescue analgesia demand
Time Frame: This will be the number of patients requiring resuce analgesia in 24h post operative period. Rescue analgesia will be administered if VAS score >4
Secondary Outcomes
No secondary outcomes reported
Investigators
Nimrah Iqbal
Principal Investigator
Rawalpindi Medical College