Surgical Treatment of Long Bone Metastases
- Conditions
- Bone MetastasesSurgery
- Registration Number
- NCT03188926
- Lead Sponsor
- Istituto Ortopedico Rizzoli
- Brief Summary
To provide treatment guidelines for patients with long bone metastatic disease based on observational study and to propose an algorithm to guide orthopedic surgeons in decision-making for these patient.
- Detailed Description
The objectives of this study were to examine clinical outcomes after reconstruction with intramedullary fixation (IMN) or endoprosthetic reconstruction (EPR) with a specific focus on (1) the rate of complication or failure; (2) differences in complication rates by anatomic site; (3) functional results as assessed by the Musculoskeletal Tumor Society System (MSTS); (4) differences in complication rate between patients treated with INM versus EPR; and (5) differences in survival in patients with metastatic bone disease based on disease-specific, laboratory, and demographic information.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 120
- bone metastases of the extremity
- bone metastases of the spine
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Clinical outcomes after treatment of long bone metastases with intramedullary nail versus endoprosthetic reconstruction 1 year The objectives of this study were to examine clinical outcomes after reconstruction with intramedullary nail versus endoprosthetic reconstruction with a specific focus on differences in complication rate between patients treated with intramedullary nail versus endoprosthetic reconstruction
- Secondary Outcome Measures
Name Time Method Survival in patients undergoing surgery for metastatic bone disease 1 year Provide a reliable and objective means of estimating survival in patients with metastatic bone disease based on disease-specific
Trial Locations
- Locations (1)
Istituto Ortopedico Rizzoli
🇮🇹Bologna, Italy