Does Preeclampsia Affect Blood Loss During a Caesarean Procedure
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 120
- 试验地点
- 1
- 主要终点
- Blood-Loss
研究概览
简要总结
Study of blood loss in preeclamptic patients using mathematical formulae
详细描述
Pre-eclampsia is a symptom complex that occurs in 2-5% of all pregnancies and leads to significant morbidity and mortality. It is associated with a risk of impaired coagulation caused by a reduced platelet count, very rarely by disseminated intravascular coagulation disorders. The degree of clotting correlates with the severity of preeclampsia. It is planned to calculate the blood loss using mathematical formulas and to compare the different blood loss in the two groups (preeclampsia vs. healthy pregnant women). Furthermore, this project will try to correlate the blood loss with the underlying coagulation situation. The aim is to be able to better assess the bleeding risk in healthy pregnant women, but also in pre-eclamptic patients in the future.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Elective or urgent caesarean section
- •Written informed consent
排除标准
- •Emergency caesarean section
- •Familial coagulation disorder
- •Hematological disorders that affect the platelet count, e.g. myelodysplastic syndrome (MDS)
- •Taking anticoagulants
- •Taking aspirin in the last 14 days
- •Use of NSARs in the last 24 hours
结局指标
主要结局
Blood-Loss
时间窗: day 1
Corelation between blood loss and coagulation parameters will be calculated
次要结局
- Coagulation parameter(day 1)