eedle based CLE in thoracic lymph nodes, a comparison with pathology.
Completed
- Conditions
- Intrathoracic lymphadenopathy1002532310029107
- Registration Number
- NL-OMON43854
- Lead Sponsor
- Academisch Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 20
Inclusion Criteria
- suspected or proved NSCLC, with an indication for EUS-FNA for tissue verification of suspected mediastinal lymph nodes.
- Suspected sarcoidosis stage I-II, with an indication of tissue verification of enlarged mediastinal lymph node(s) by EUS-FNA.
Exclusion Criteria
- Allergy for fluorescein
- Use of Beta blocker on the day of the procedure
- (Possible) pregnancy or lactation
- Inability to provide informed consent
- Inability to comply with study protocol
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>1 To describe characteristics and define interpretation criteria for nCLE<br /><br>imaging of:<br /><br>- normal/reactive lymph nodes<br /><br>- lymph nodes involved in lungcancer<br /><br>- lymph nodes involved in sarcoidosis</p><br>
- Secondary Outcome Measures
Name Time Method <p>1. To develop an CLE image atlas for lymph nodes involved in different pulmonal<br /><br>diseases<br /><br>2.To assess procedure-related events of needle based CLE<br /><br>3. To assess technical feasibility of needle based CLE</p><br>