The effectiveness of an epidermal growth factor containing cream on postinflammatory hyperpigmentation after 1064 nm Q-switched Nd:YAG laser treatment of Hori nevus in Asians

Phase 2

Completed

• Conditions: Participants with symmetrical Hori nevus; Epidermal growth factor; Postinflammatory hyperpigmentation; 1,064-nm Q-switched Nd:YAG laser; Hori nevus

• Registration Number: TCTR20210301001
• Lead Sponsor: Division of Dermatology Ramathibodi hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2020-01-31
• Study Start: 2021-03-01
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

1 Healthy participants
2 Symmetrical Hori nevus
3 Aged 18-60 years

Exclusion Criteria

1 History of laser, light therapy for Hori nevus
2 History of topical bleaching agents or chemical peels < 4 wk
3 An active facial skin infection/inflammation
4 History of recurrent herpes infection
5 Immunocompromised host
6 Pregnancy or breast feeding

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Postinflammatory hyperpigmentation at 4 and 8 weeks after intervention started melanin index

Secondary Outcome Measures

Name	Time	Method
postlaser erythema at 1, 3, 7 days after intervention started erythema index,skin barrier function at 1, 3, 7 days after intervention started transepidermal water loss