Stress, Obesity, Liver fat, Insulin resistance in Depressio

• Conditions: F32; F33; Depressive episode; Recurrent depressive disorder

• Registration Number: DRKS00004324
• Lead Sponsor: Zentralinstitut für Seelische Gesundheit

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2012-08-21
• Study Completion: 2013-02-01
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 58

Inclusion Criteria

Patients: depressive episode (unipolar), severity: HDRS >= 18

Exclusion Criteria

Patients and controls:
not competent for consent, insufficient german language, diabetes, dyslipidemia, contraindication for MRI

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
This is a non-interventional trial. The above-mentioned dependent variables will be compared between healthy controls and depressed patients as well as between subgroups of depressed patients (e.g. high vs. low activity of the HPA system): functional imaging of the brain (MRI), breast and abdominal imaging (MRI), blood analysis for metabolic and genetic parameters, dexamethasone suppression test, cortisol in saliva and urine. This is a cross-sectional trial.