Depth of Invasion in oral cancer - Is clinical examination valid?
Not Applicable
- Conditions
- Health Condition 1: C069- Malignant neoplasm of mouth, unspecified
- Registration Number
- CTRI/2019/12/022485
- Lead Sponsor
- All india Institute of Medical Sciences Bhubaneswar
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.Histopathologicalevidence of squamous cell carcinoma in oral cavity.
2.Patients giving consent for the planned oral surgery.
3.Clinically T1- T3 lesions as per AJCC 8th edition
Exclusion Criteria
1.Tumors of other than squamous histology.
2.Patients who have receivedChemotherapy/ Radiation therapy
3.Patients having undergone excision biopsy
4.Not undergone MRI as imaging modality
5.Patients with second primary tumors.
6.Patients refusing to give consent.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To establish the correlation between clinical and histopathological assessment of depth of invasion in case of oral cancer.Timepoint: 1. Clinical Assesment Before Surgery <br/ ><br>2. After Imaging <br/ ><br>3. After Resection/Surgery <br/ ><br>4. After Fixation of Specimen
- Secondary Outcome Measures
Name Time Method To estimate the extent of tumor shrinkage in formalin fixed specimen. <br/ ><br> <br/ ><br>Timepoint: 1. After Resection/Surgery <br/ ><br>2. After Fixation of Specimen <br/ ><br>;To estimate the surgical margin shrinkage in formalin fixed specimen.Timepoint: 1. Intraoperatively <br/ ><br>2. After Resection/Surgery <br/ ><br>3. After Fixation of Specimen;To study the correlation between pattern of invasion with grade of disease, nodal status and final stage of the disease.Timepoint: 1. Clinical Assesment Before Surgery <br/ ><br>2. After Imaging <br/ ><br>3. After Fixation of Specimen