Color Doppler Imaging of Orbital Venous Flow in Grave's Orbitopathy

Completed

• Conditions: Graves' Disease; Graves' Ophthalmopathy

• Registration Number: NCT00697528
• Lead Sponsor: University of Sao Paulo

Brief Summary

Orbital Venous flow study in patients with Grave's Orbitopathy in different manifestation forms and stages, made with Color Doppler Imaging

Detailed Description

Prospective study with Grave's patients in active and fibrotic disease, myogenic and lipogenic forms, with muscle restriction and without muscle restriction and with or without optic compressive neuropathy. Blood flow was studied with Color Doppler Imaging (CDI) in the following orbital vessels:

* Superior Ophthalmic Vein (main target of the study protocol)

* Retinal Central Vein

* Retinal Central Artery

* Ophthalmic Artery

Study Timeline

• Study Start: 2007-01
• Status Verified: 2008-06
• Study First Submitted: 2008-06-11
• Study First Submitted QC: 2008-06-13
• Study First Posted: 2008-06-16
• Primary Completion: 2008-12
• Study Completion: 2008-12
• Last Update Submitted: 2013-12-18
• Last Update Posted: 2013-12-19

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 66

Inclusion Criteria

• Clinical diagnosis of Grave's Orbitopathy with well defined disease.

Exclusion Criteria

• Uncertain cases, with an undefined status of Grave's Ophthalmopathy.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Trial Locations

Locations (1)

Hospital das Clínicas da Universidade São Paulo; 🇧🇷 São Paulo, Brazil