Treatment Outcomes of Nebulized High-dose Inhaled Corticosteroid as Add-on Therapy in Asthma Exacerbation at Emergency Department: A Randomized Controlled Trial

Phase 4

Completed

• Conditions: acute asthma exacerbation; acute asthma exacerbation, emergency department, high dose inhaled corticosteroids, randomize controlled trial

• Registration Number: TCTR20201214001
• Lead Sponsor: Faculty of Medicine Thammasat university

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2020-12-14
• Study Completion: 2023-04-30
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 88

Inclusion Criteria

Emergency department patient who diagnosed of acute asthma exacerbation

Exclusion Criteria

1. respiratory failure who require intubation
2. history of corticosteroids allergy
3. diagnosis of COVID-19, pulmonary TB, and pneumonia
4. patients who refuse to participate

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
treatment outcomes 48 hours length of ED stay, ED revisit with in 48 hrs after ED discharge and admission rate

Secondary Outcome Measures

Name	Time	Method
treatment outcomes 48 hours after ED discharge dyspnea scale, pulmonary functions, length of hospital stay, and home exacerbation after ED discharge