albuphine versus clonidine with hyperbaric bupivacaine for spinal anaesthesia
Not Applicable
Completed
- Conditions
- Health Condition 1: S899- Unspecified injury of lower leg
- Registration Number
- CTRI/2018/12/016742
- Lead Sponsor
- niversity College of Medical Sciences and Guru Teg Bahadur Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 63
Inclusion Criteria
Patients belonging to ASA grade I and II who are undergoing orthopedic lower limb surgery with height of >150cm and <180cm.
Exclusion Criteria
1.Patients with known allergy to drugs involved in the study.
2.Patients with contraindications to central neuraxial block like patients with coagulations abnormalities, increased intracranial pressure, local sepsis in spinal lumbar region.
3.Patients with weight >120kg.
4.Patient with history of chronic pain or long term opioid use.
5.Patient refusal.
6.Multiple fractures precluding assessment of anaesthesia.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The duration of analgesia following intrathecal test drug solution administrationTimepoint: 0,2,4,8,10,15,20 and 30 minutes following drug administration and then every 15 minutes during intra operative period and every 30 minutes dring 2 hours of post operative period
- Secondary Outcome Measures
Name Time Method 1.Time of onset, maximum level, time to achieve maximum level and duration of sensory block <br/ ><br>2.Time of onset, intensity and duration of motor block <br/ ><br>3.Postoperative pain assessment (VAS) and total analgesic requirement in first 24 hours <br/ ><br>Timepoint: 0,2,4,8,10,15,20 and 30 minutes following drug administration and then every 15 minutes during intra operative period and every 30 minutes dring 2 hours of post operative period and then at 4th,8th,12th hour and 24 hours respectively